The Hippo Kinase LATS2 Controls Helicobacter pylori-Induced Epithelial-Mesenchymal Transition and Intestinal Metaplasia in Gastric Mucosa
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چکیده
منابع مشابه
Helicobacter pylori, intestinal metaplasia, and the accuracy of biopsies in metaplastic gastric mucosa
The identification and eradication of Helicobacter Pylori (HP) is vital to prevent gastric cancer. After the detection of the HP colonization, accompanying histopathological findings belonging the gastric carcinogenesis should also be considered. According to the widely accepted proofs, although the presence of HP colonization initiates the sequential changes of carcinogenesis, the success rate...
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To determine whether there is a relationship between the presence of H pylori and the various subtypes of intestinal metaplasia in the gastric antrum, 2274 antral gastroscopic biopsies from 533 patients were examined. H pylori was found in 289 patients. Intestinal metaplasia in general was found in 135 patients. Type I intestinal metaplasia was found in 133 patients (98.5%), type II in 106 pati...
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Helicobacter pylori (H. pylori) induces chronic gastric inflammation, atrophic gastritis, intestinal metaplasia, and cancer. Although the risk of gastric cancer increases exponentially with the extent of atrophic gastritis, the precise mechanisms of gastric carcinogenesis have not been fully elucidated. H. pylori induces genetic and epigenetic changes in gastric epithelial cells through activat...
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ژورنال
عنوان ژورنال: Cellular and Molecular Gastroenterology and Hepatology
سال: 2020
ISSN: 2352-345X
DOI: 10.1016/j.jcmgh.2019.10.007